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No es este el significado original de la palabra. Si he escogido estos temas concretos es por dos razones principales. En cada uno de los casos, abordo el tema central desde dos perspectivas bastante distintas, aunque complementarias. Lo principal, en cualquier caso, es que a lo largo del camino descubriremos que los errores no solo son inevitables sino que constituyen una parte esencial del progreso de la ciencia.

El desarrollo de la ciencia no es una andadura directa hacia la verdad. Vivimos en un planeta diminuto que da vueltas en torno a una estrella normal y corriente de una galaxia que contiene cientos de miles de millones de estrellas parecidas.

O sea, que no tenemos nada de especial. Los humanos evolucionaron del mismo modo que cualquier otro organismo. De manera equivalente, en el esquema evolutivo de Darwin, todos los organismos vivos en la actualidad, incluidos los humanos, son el producto de rutas evolutivas parecidas. Todos los seres vivos de la Tierra forman parte de la misma gran familia. Darwin nos ha obligado a repensar la naturaleza del mundo y de los humanos. Por ejemplo, la hembra del pez luna Mola mola produce hasta trescientos millones de huevos de cada vez.

El entorno es el agente que sacude el cedazo. Como los organismos compiten por unos recursos limitados, algunos sobreviven y otros no. William Schwenck Gilbert, The Gondoliers. Figura 5 y 6 Figura 26a y 26b. Sin embargo, no parece que, al menos en un principio, a Darwin se le ocurriera apelar a esta idea de la latencia en sus intentos por responder a Jenkin.

En uno, admite abiertamente: No puedo entender de otro modo que las formas resultantes de los cruces reviertan con tanta frecuencia a formas ancestrales. Pero todo esto, naturalmente, es infinitamente tosco. No creo que entienda usted lo que quiero decir al referirme a ciertas variedades que no se mezclan.

No se trata de la fertilidad. Esta carta es notable en dos aspectos. Para acabar de entender la actitud de Darwin hacia la herencia particulada, hay unas cuantas preguntas inquietantes a las que hay que dar respuesta. Esto, sin embargo, plantea otra interesante pregunta: Haldane y Sewall Wright.

Los humanos han sentido curiosidad por la edad de la Tierra desde el principio de la historia. En otras palabras, la Tierra de Lyell se encontraba casi en un estado estacionario , y sobre ella, a paso de caracol, actuaban cambios a lo largo de un tiempo casi infinito. Sin embargo, comenzaba a cocerse una controversia. Se pueden contar las toneladas. No puede haber uniformidad. No obstante, el trabajo de Darwin fue revelador en otro sentido: La respuesta es muy simple.

Una cosa hay que dejar clara: Huxley amaba la controversia tanto como Darwin la detestaba. Al menos una de las razones del deterioro posterior del estatus de Kelvin tiene que ver con el debate sobre la edad de la Tierra: La ciencia solo se vuelve peligrosa cuando cree que ha alcanzado su objetivo. Pero la ciencia raramente progresa exactamente como se espera. La figura 11 representa su intento de reconstruir el trozo de papel original de A Pauling se le presentaba ahora un dilema: Mi mente estaba perpleja.

Las contribuciones de Pauling a nuestro conocimiento de la naturaleza de la vida fueron considerables. Watson y Crick estaban a punto de aplicar el mismo enfoque para descubrir la estructura del ADN. Thomas Hunt Morgan y sus colaboradores reconocieron esas unidades en los genes que se disponen linealmente en los cromosomas.

Sin embargo, este caso me parece demasiado improbable para tener una validez general, si no es de la siguiente manera. Las cuatro bases eran: Acabaron trabajando por separado aunque compartieran los mismos laboratorios.

En palabras de Crick: Hacia el fin de , los acontecimientos comenzaron a sucederse con rapidez. El 21 de noviembre de Watson hizo un viaje a Londres para escuchar un coloquio de Rosalind Franklin.

La respuesta fue inmediata: El fiasco tuvo consecuencias importantes: Ha sido habitual suponer que los directores de los dos laboratorios, Randall y Bragg, acordaron una moratoria respecto a nuevas investigaciones sobre el ADN por parte de Watson y Crick.

En una carta formal fechada el 11 de diciembre de , Maurice Wilkins le escribe a Crick: Uno de los argumentos que se aducen es que sus ideas se derivan directamente de afirmaciones realizadas durante un coloquio y eso me parece tan convincente como su propio argumento de que su enfoque viene bastante de la nada. Somos dos Unidades del M.

Entretanto, Franklin estaba haciendo progresos importantes. Pero el 14 de febrero de , Ruth B. Pero lo cierto es que todas esas especulaciones son bastante irrelevantes. Viajaron a bordo del famoso Queen Mary. Sin embargo, ni siquiera entonces estaba preparado para sumergirse de lleno otra vez en el problema del ADN. En palabras de Peter: A mi derecha estaba la mesa que de vez en cuando ocupaba Jim Watson.

No hay nada que hacer. Las calamidades son de dos tipos: A Watson y Crick les costaba aceptar la enormidad de aquel error. Claramente, este principio de autocomplementariedad [] sugiere fuertemente una arquitectura basada en dos hebras, y era marcadamente incongruente con una estructura de tres hebras. Todo el mundo utiliza el razonamiento inductivo [] continuamente, y suele ayudarnos a tomar decisiones correctas a partir de datos relativamente pobres. Supongamos, por ejemplo, que nos piden que completemos esta frase: En consecuencia, la gente tiende a arriesgar cuando se le presenta un encuadre negativo.

El olvido de las reglas de Chargaff es, a mi entender, menos misterioso. Por tanto, que Pauling no recordase las reglas de Chargaff no es demasiado sorprendente.

No tengas miedo a equivocarte. Cada cual puede formarse su propio juicio. Lo que escribieron fue: Wilkins, la doctora R. Los primeros intentos fueron infructuosos. La figura 16 muestra el lugar en el Eagle donde Crick hizo su anuncio. Figura 15 y Figura La figura 20 muestra a Eddington con Einstein en Cambridge. Eddington era plenamente consciente de esta evidente discrepancia. La idea era genial en su claridad. La idea era alucinante: Pensemos en esto por un momento: A fin de cuentas, el carbono no solo era relativamente abundante en el universo, sino crucial para la vida.

Los resultados eran claros. Y acaban con un reconocimiento: Sea la masa dos; y fue la masa dos. Y vio Dios el deuterio y vio que era bueno. Sea la masa tres. Las estrellas pasan la vida en continua lucha con la gravedad. La primera, de El rey Lear , dice: El resto, como se suele decir, ya es historia. Esta es la gran pregunta que plantearon Hoyle, Bondi y Gold en La figura 24 muestra el cartel original del filme.

Figuras 26a y 26b. De este modo, razonaba Hoyle, el universo se mantiene en un estado estacionario. En el escenario evolutivo a la izquierda , al pasar un tiempo las galaxias se han alejado unas de otras abajo a la izquierda , reduciendo la densidad global de materia.


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